Article
p53 alteration and human papilloma virus infection in paranasal sinus cancer.
Cancer - 1 Apr 1997
Caruana S M, Zwiebel N, Cocker R, McCormick S A, Eberle R C, Lazarus P
Abstract excerpt
BACKGROUND: Inverted papilloma (IP) of the paranasal sinus is a benign neoplastic condition that can be associated with squamous cell carcinoma (SCC). To understand the etiology of the disease better, paranasal sinus tumor specimens were examined for alterations in either p53 protein expression or genomic DNA sequence, and for infection by human papilloma virus (HPV). METHODS: Tumor specimens were categorized as...
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