Article
Premature translational termination triggers mRNA decapping.
Nature - 18 Aug 1994
Muhlrad D, Parker R
Abstract excerpt
The degradation of messenger RNA in eukaryotic cells is initiated by endonucleolytic cleavage or by shortening of the poly(A) tail, which for some mRNAs activates a deadenylation-dependent decapping reaction. One type of rapid mRNA degradation in eukaryotes is caused by premature termination of t...
Topics
- Adenosine Monophosphate
- Base Sequence
- Codon
- Molecular Sequence Data
- Mutation
- Peptide Chain Termination, Translational
- Phosphoglycerate Kinase
- RNA Caps
- Saccharomyces cerevisiae
- Transcription, Genetic