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Article

In plants, decapping prevents RDR6-dependent production of small interfering RNAs from endogenous mRNAs.

Nucleic acids research - 11 Mar 2015

Martínez de Alba Angel Emilio, Moreno Ana Beatriz, Gabriel Marc, Mallory Allison C, Christ Aurélie, Bounon Rémi, Balzergue Sandrine, Aubourg Sebastien, Gautheret Daniel, Crespi Martin D, Vaucheret Hervé, Maizel Alexis

Abstract excerpt

Cytoplasmic degradation of endogenous RNAs is an integral part of RNA quality control (RQC) and often relies on the removal of the 5' cap structure and their subsequent 5' to 3' degradation in cytoplasmic processing (P-)bodies. In parallel, many eukaryotes degrade exogenous and selected endogenous RNAs through post-transcriptional gene silencing (PTGS). In plants, PTGS depends on small interfering (si)RNAs...

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PMID: 25694514
DOI: 10.1093/nar/gkv119
PMCID: PMC4357720

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Source receipt: pubmed, retrieved 7 Sept 2026.

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