Article
Lack of association between apolipoprotein E allele epsilon 4 and sporadic Alzheimer's disease.
Neuroscience letters - 14 Mar 1994
Lannfelt L, Lilius L, Nastase M, Viitanen M, Fratiglioni L, Eggertsen G, Berglund L, Angelin B, Linder J, Winblad B
Abstract excerpt
Apolipoprotein E (apoE) is a protein involved in the transport of lipids and a component of Alzheimer's disease (AD) plaques. There are three common alleles of the apoE gene, designated epsilon 2, epsilon 3 and epsilon 4. An association between familial and sporadic AD and the epsilon 4 allele was recently reported. We have investigated Swedish Alzheimer patients and controls. The epsilon 4 allele frequency in...
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