Article
Lack of an association between apolipoprotein E epsilon 4 and Alzheimer's disease in elderly Nigerians.
Annals of neurology - 1 Sept 1995
Osuntokun B O, Sahota A, Ogunniyi A O, Gureje O, Baiyewu O, Adeyinka A, Oluwole S O, Komolafe O, Hall K S, Unverzagt F W
Abstract excerpt
As part of a community-based study of Alzheimer's Disease (AD) in a Nigerian population aged 65 years and over, we have determined apolipoprotein E (APOE) genotypes on 56 subjects (39 controls and 17 subjects with dementia, including 12 with AD). The epsilon 4 allele of APOE was not associated with AD or dementia in this community-based sample. The epsilon 4 allele frequency was 17.6% in demented patients and...
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