Article
Allelic differences in TCR gamma-chains alter gamma delta T cell antigen reactivity.
Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 1994
Kalataradi H, Eyster C L, Fry A, Vollmer M K, Fu Y X, Born W K, O'Brien R L
Abstract excerpt
Mouse gamma delta T cell hybridomas from various strains that express a TCR-V gamma 1/V delta 6 respond weakly to an autologous Ag and more strongly to a short segment of the mycobacterial heat shock protein-60 (HSP-60). However, V gamma 1/V delta 6 hybridomas derived from AKR mice show greatly reduced or absent responses to these stimuli. To determine whether the lack of response in these AKR hybridomas is...
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