Article
TCR diversity in gammadeltaTCR+ hybridomas derived from mice given portal vein donor-specific pre-immunization and skin allografts.
Immunology letters - 1 Dec 1998
Sun Y, Chen Z, Chung S W, Zeng H, Gorczynski R M
Abstract excerpt
Portal venous (p.v.) immunization with multiple minor histoincompatible cells leads to antigen-specific increased skin allograft survival. GammadeltaTCR+ hybridoma cells, prepared from mesenteric lymphocytes of p.v. immunized animals, can adoptively transfer this increased graft survival to naive...
Topics
- Adoptive Transfer
- Amino Acid Sequence
- Animals
- Base Sequence
- Cytokines
- DNA, Complementary
- Genetic Variation
- Graft Survival
- Hybridomas
- Immunization
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Molecular Sequence Data
- Portal Vein
- Receptors, Antigen, T-Cell, gamma-delta
- Reverse Transcriptase Polymerase Chain Reaction