Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Atypical regions in large genomic DNA sequences.

Proceedings of the National Academy of Sciences of the United States of America - 19 Jul 1994

Scherer S, McPeek M S, Speed T P

Abstract excerpt

Large genomic DNA sequences contain regions with distinctive patterns of sequence organization. We describe a method using logarithms of probabilities based on seventh-order Markov chains to rapidly identify genomic sequences that do not resemble models of genome organization built from compilations of octanucleotide usage. Data bases have been constructed from Escherichia coli and Saccharomyces cerevisiae DNA...

Topics

Bacteriophage lambda
Base Sequence
DNA
Genetic Variation
Globins
Humans
Information Systems
Markov Chains
Saccharomyces
Sequence Analysis, DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 8041759
DOI: 10.1073/pnas.91.15.7134
PMCID: PMC44353

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8041759-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Atypical regions in large genomic DNA sequences.PMID 8041759Read ↗

Computational DNA sequence analysis.Semantic proximity Read ↗

Absent from DNA and protein: genomic characterization of nullomers and nullpeptides across functional categories and evolutionSemantic proximity Read ↗

Significant non-existence of sequences in genomes and proteomes.Semantic proximity Read ↗

Abundant oligonucleotides common to most bacteria.Semantic proximity Read ↗

A statistical method for detecting regions with different evolutionary dynamics in multialigned sequences.Semantic proximity Read ↗

Implications of human genome structural heterogeneity: functionally related genes tend to reside in organizationally similar genomic regions.Semantic proximity Read ↗

Analysis of gene order conservation in eukaryotes identifies transcriptionally and functionally linked genes.Semantic proximity Read ↗

G4 motifs in human genes.Semantic proximity Read ↗

Open questions: a logic (or lack thereof) of genome organization.Semantic proximity Read ↗

Assessments of DNA inhomogeneities in yeast chromosome III.Semantic proximity Read ↗

Cryptic simplicity in DNA is a major source of genetic variation.Semantic proximity Read ↗

Investigations of oligonucleotide usage variance within and between prokaryotes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.