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Article

Implications of human genome structural heterogeneity: functionally related genes tend to reside in organizationally similar genomic regions.

BMC genomics - 31 Mar 2014

Paz Arnon, Frenkel Svetlana, Snir Sagi, Kirzhner Valery, Korol Abraham B

Abstract excerpt

BACKGROUND: In an earlier study, we hypothesized that genomic segments with different sequence organization patterns (OPs) might display functional specificity despite their similar GC content. Here we tested this hypothesis by dividing the human genome into 100 kb segments, classifying these segments into five compositional groups according to GC content, and then characterizing each segment within the five...

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Identifiers

PMID: 24684786
DOI: 10.1186/1471-2164-15-252
PMCID: PMC4234528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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