Article
Computational DNA sequence analysis.
Annual review of microbiology - 1 Jan 1994
Karlin S, Cardon L R
Abstract excerpt
This paper reviews several new developments in computer and statistical analysis of DNA and protein sequences. We present criteria and describe means for assessing and interpreting genomic inhomogeneities within and between sequences. These include: (a) characterizations of short oligonucleotide biases and general compositional tendencies; (b) molecular evolutionary reconstructions based on dinucleotide relative...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- DNA
- Genetic Variation
- Humans
- Models, Statistical
- Molecular Sequence Data
- Oligonucleotides
- Phylogeny
- Sequence Analysis, DNA
