Article
A statistical method for detecting regions with different evolutionary dynamics in multialigned sequences.
Molecular phylogenetics and evolution - 1 Jun 1992
Pesole G, Attimonelli M, Preparata G, Saccone C
Abstract excerpt
We describe a stochastic method for tracing the evolutionary pattern of multialigned sequences. This method allows us to detect gene regions with distinct evolutionary dynamics, e.g., regions that significantly deviate from the expected behavior. Accurate detection of hypervariable or hyperconstrained regions may provide useful information on the structure/function relationship of biosequences. This information...
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