A statistical method for detecting regions with different evolutionary dynamics in multialigned sequences.

doi:10.1016/1055-7903(92)90023-a

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Article

A statistical method for detecting regions with different evolutionary dynamics in multialigned sequences.

Molecular phylogenetics and evolution - 1 Jun 1992

Pesole G, Attimonelli M, Preparata G, Saccone C

Abstract excerpt

We describe a stochastic method for tracing the evolutionary pattern of multialigned sequences. This method allows us to detect gene regions with distinct evolutionary dynamics, e.g., regions that significantly deviate from the expected behavior. Accurate detection of hypervariable or hyperconstr...

Topics

Animals
Biological Clocks
Biological Evolution
Biometry
Cytochrome b Group
Genetic Variation
Globins
Humans
Models, Genetic
Sequence Alignment
Stochastic Processes

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