Analysis of gene order conservation in eukaryotes identifies transcriptionally and functionally linked genes.

doi:10.1371/journal.pone.0010654

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Article

Analysis of gene order conservation in eukaryotes identifies transcriptionally and functionally linked genes.

PloS one - 14 May 2010

Dávila López Marcela, Martínez Guerra Juan José, Samuelsson Tore

Abstract excerpt

The order of genes in eukaryotes is not entirely random. Studies of gene order conservation are important to understand genome evolution and to reveal mechanisms why certain neighboring genes are more difficult to separate during evolution. Here, genome-wide gene order information was compiled for 64 species, representing a wide variety of eukaryotic phyla. This information is presented in a browser where gene...

Topics

Conserved Sequence
DNA, Intergenic
Eukaryota
Evolution, Molecular
Fungi
Gene Order
Genetic Linkage
Genetic Variation
Genome, Human
Humans
Phylogeny
Promoter Regions, Genetic
Transcription, Genetic

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Identifiers

PMID: 20498846
DOI: 10.1371/journal.pone.0010654
PMCID: PMC2871058

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