Molecular genetic profiles of colitis-associated neoplasms.

doi:10.1016/0016-5085(94)90167-8

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Article

Molecular genetic profiles of colitis-associated neoplasms.

Gastroenterology - 1 Aug 1994

Kern S E, Redston M, Seymour A B, Caldas C, Powell S M, Kornacki S, Kinzler K W

Abstract excerpt

BACKGROUND/AIMS: A major long-term risk for patients with chronic idiopathic colitis is the development of colorectal dysplasia and adenocarcinoma. The presence or absence of specific genetic changes in these lesions will provide important insights into the relationship of colitis-associated dysp...

Topics

Adenocarcinoma
Adult
Aged
Alleles
Colitis
Colon
Colorectal Neoplasms
Genes, APC
Genes, p53
Genes, ras
Humans
Immunohistochemistry
Middle Aged
Mutation
Retinoblastoma Protein

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