Article
Molecular genetic profiles of colitis-associated neoplasms.
Gastroenterology - 1 Aug 1994
Kern S E, Redston M, Seymour A B, Caldas C, Powell S M, Kornacki S, Kinzler K W
Abstract excerpt
BACKGROUND/AIMS: A major long-term risk for patients with chronic idiopathic colitis is the development of colorectal dysplasia and adenocarcinoma. The presence or absence of specific genetic changes in these lesions will provide important insights into the relationship of colitis-associated dysplasia and the development of carcinoma. METHODS: A case-study approach was used to develop detailed molecular genetic...
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