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Article

Genomic characterization of colitis-associated colorectal cancer.

World journal of surgical oncology - 2 Jul 2018

Kameyama Hitoshi, Nagahashi Masayuki, Shimada Yoshifumi, Tajima Yosuke, Ichikawa Hiroshi, Nakano Masato, Sakata Jun, Kobayashi Takashi, Narayanan Sumana, Takabe Kazuaki, Wakai Toshifumi

Abstract excerpt

BACKGROUND: Inflammatory bowel disease (IBD), which includes ulcerative colitis (UC) and Crohn's disease (CD), is a chronic, idiopathic, repeated inflammatory disease. Colorectal cancer (CRC) that develops in patients with IBD is known as colitis-associated colorectal cancer (CAC), but the underlying carcinogenic mechanism remains unclear. Genomic analysis of sporadic CRC has been well described based on...

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Identifiers

PMID: 29966533
DOI: 10.1186/s12957-018-1428-0
PMCID: PMC6027567

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