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The Role of Biomarkers in Surveillance of Ulcerative Colitis Associated Colorectal Cancer: A Narrative Review

2025-07-23

Abstract excerpt

Ulcerative colitis (UC) is associated with an elevated risk of colorectal cancer (CRC), driven by chronic inflammation and a distinct inflammation–dysplasia–carcinoma pathway. Conventional surveillance relies on colonoscopy and histologic assessment, but flat, multifocal dysplasia and sampling limitations challenge early detection. Tissue-based biomarkers offer promise in improving risk stratification and identify...

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Literature Corpus work
3cd185db-40e8-5b2b-9ac6-e445a4559004
DOI
10.20944/preprints202507.1913.v1
Open publication

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