Article
Molecular biology of dysplasia and cancer in inflammatory bowel disease.
Gastroenterology clinics of North America - 1 Sept 2006
Itzkowitz Steven H
Abstract excerpt
Colorectal cancer (CRC) develops from a dysplastic precursor lesion, regardless of whether it arises sporadically, in the setting of high-risk hereditary conditions, or in the context of chronic inflammation like inflammatory bowel disease (IBD). This review focuses on the molecular alterations associated with CRC pathogenesis in IBD. Although none of the molecular alterations to be discussed have yet been...
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