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Article

IBD-Associated Dysplastic Lesions Show More Chromosomal Instability Than Sporadic Adenomas

1 Aug 2019

Abstract excerpt

BACKGROUND: Patients with longstanding inflammatory bowel disease (IBD; ie, ulcerative colitis and Crohn's disease) have an increased risk of colorectal cancer (CRC). Due to ongoing inflammation, IBD-associated dysplastic lesions can develop. These lesions have an increased risk to progress to cancer compared with sporadic adenomas, which are also found in these patients. Differentiating between these 2 types of...

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PMID: 31372648
DOI: 10.1093/ibd/izz171

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