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Article

Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer.

Nature reviews. Gastroenterology & hepatology - 1 May 2009

Feagins Linda A, Souza Rhonda F, Spechler Stuart J

Abstract excerpt

In patients with IBD, chronic colonic inflammation increases the risk of colorectal cancer, perhaps because inflammation predisposes these tissues to genomic instability. Carcinogenesis in the inflamed colon seems to follow a different sequence of genetic alterations than that observed in sporadic cancers in the uninflamed colon. In this Review, we focus on the genetic alterations in colitis-associated colorectal...

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Identifiers

PMID: 19404270
DOI: 10.1038/nrgastro.2009.44

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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