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Genetic alterations in human gastric cancer.

Cancer cells (Cold Spring Harbor, N.Y. : 1989) - 1 Feb 1991

Hirohashi S, Sugimura T

Abstract excerpt

Most types of human tumors display a consistent set of genetic alterations that are thought to play a role in tumor development and progression. In the case of gastric carcinomas, consistent genetic changes have been difficult to identify because (1) the tumor DNA samples are often heavily contaminated with DNA from normal stromal cells and (2) the tumors are heterogeneous in origin. However, with the recent...

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PMID: 2029453

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