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Article

Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study.

Cancer research - 1 Aug 1994

Brockmöller J, Kerb R, Drakoulis N, Staffeldt B, Roots I

Abstract excerpt

Glutathione S-transferase M1 (GSTM1) is a foreign compound-metabolizing enzyme with a heritable complete lack of activity in about 50% of Caucasians. GSTM1 deficiency may predispose individuals to urinary bladder cancer. Thus, a hospital-based case-control study was performed with 296 patients with bladder cancer and 400 controls, investigating this GSTM1 deficiency in relation to environmental risk factors and...

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Identifiers

PMID: 8033143

Genes

GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study.PMID 8033143Read ↗

Glutathione S-transferase mu1 (GSTM1) status and bladder cancer risk: a meta-analysis.Semantic proximity Read ↗

The role of human glutathione S-transferases M1 and T1 in individual susceptibility to bladder cancer.Semantic proximity Read ↗

Genetic polymorphisms of glutathione S-transferase M1 and bladder cancer risk: a meta-analysis of 26 studies.Semantic proximity Read ↗

Susceptibility to urinary bladder cancer: relevance of rs9642880[T], GSTM1 0/0 and occupational exposure.Semantic proximity Read ↗

Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer.Semantic proximity Read ↗

GSTA1, GSTM1, GSTP1, and GSTT1 polymorphisms and susceptibility to smoking-related bladder cancer: a case-control study.Semantic proximity Read ↗

Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer.Semantic proximity Read ↗

A germline homozygote deletion of the glutathione-S-transferase Mu1 gene predisposes to bladder cancer.Semantic proximity Read ↗

Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review.Semantic proximity Read ↗

Genetic polymorphism in bladder cancer.Semantic proximity Read ↗

Genetic polymorphism of glutathione S-transferases M1 and T1 as a risk factor in lung and bladder cancers.Semantic proximity Read ↗

Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology.Semantic proximity Read ↗

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