Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study.

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study.

Cancer research - 1 Aug 1994

Brockmöller J, Kerb R, Drakoulis N, Staffeldt B, Roots I

Abstract excerpt

Glutathione S-transferase M1 (GSTM1) is a foreign compound-metabolizing enzyme with a heritable complete lack of activity in about 50% of Caucasians. GSTM1 deficiency may predispose individuals to urinary bladder cancer. Thus, a hospital-based case-control study was performed with 296 patients with bladder cancer and 400 controls, investigating this GSTM1 deficiency in relation to environmental risk factors and...

Topics

Aged
Alleles
Base Sequence
Case-Control Studies
Coenzymes
Female
Genotype
Glutathione Transferase
Humans
Male
Middle Aged
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Occupational Exposure

Occupations

Odds Ratio

Phenotype

Polymerase Chain Reaction

Smoking

Source

Open in PubMed

Identifiers

PMID: 8033143

Genes

GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8033143-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study.PMID 8033143Read ↗

Glutathione S-transferase mu1 (GSTM1) status and bladder cancer risk: a meta-analysis.Semantic proximity Read ↗

The role of human glutathione S-transferases M1 and T1 in individual susceptibility to bladder cancer.Semantic proximity Read ↗

Genetic polymorphisms of glutathione S-transferase M1 and bladder cancer risk: a meta-analysis of 26 studies.Semantic proximity Read ↗

Susceptibility to urinary bladder cancer: relevance of rs9642880[T], GSTM1 0/0 and occupational exposure.Semantic proximity Read ↗

Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer.Semantic proximity Read ↗

GSTA1, GSTM1, GSTP1, and GSTT1 polymorphisms and susceptibility to smoking-related bladder cancer: a case-control study.Semantic proximity Read ↗

Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer.Semantic proximity Read ↗

A germline homozygote deletion of the glutathione-S-transferase Mu1 gene predisposes to bladder cancer.Semantic proximity Read ↗

Pooled analysis and meta-analysis of glutathione S-transferase M1 and bladder cancer: a HuGE review.Semantic proximity Read ↗

Genetic polymorphism in bladder cancer.Semantic proximity Read ↗

Genetic polymorphism of glutathione S-transferases M1 and T1 as a risk factor in lung and bladder cancers.Semantic proximity Read ↗

Relevance of the deletion polymorphisms of the glutathione S-transferases GSTT1 and GSTM1 in pharmacology and toxicology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.