Article
Polymorphic deletions of the GSTT1 and GSTM1 genes and susceptibility to bladder cancer.
BJU international - 1 Jun 2011
Salinas-Sánchez Antonio S, Sánchez-Sánchez Francisco, Donate-Moreno María J, Rubio-del-Campo Antonio, Gimenez-Bachs José M, Lorenzo-Romero Juan G, Serrano-Oviedo Leticia, Escribano Julio
Abstract excerpt
UNLABELLED: What's known on the subject? and What does the study add? Bladder cancer susceptibility may be determined by genetic differences in the activity of glutathione S-transferases, enzymes that regulate the conversion of exogenous carcinogens to excretable hydrophilic metabolites by glutathione conjugation. The discrepancy of results regarding the association of common genetic polymorphisms and complex...
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