Article
The role of human glutathione S-transferases M1 and T1 in individual susceptibility to bladder cancer.
Physiological research - 1 Jan 1999
Salagovic J, Kalina I, Habalová V, Hrivnák M, Valanský L, Biros E
Abstract excerpt
Several genes involved in the metabolism of carcinogens have been found to be polymorphic in the human population, and specific alleles are associated with increased risk of cancer at various sites. This study is focused on the polymorphic enzymes glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) that are involved in the detoxification of many xenobiotics involved in the etiology of bladder cancer. To...
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