Genetic polymorphism of glutathione S-transferases M1 and T1 as a risk factor in lung and bladder cancers.

Article

Genetic polymorphism of glutathione S-transferases M1 and T1 as a risk factor in lung and bladder cancers.

Neoplasma - 1 Jan 1998

Salagovic J, Kalina I, Stubna J, Habalová V, Hrivnák M, Valanský L, Kohút A, Biros E

Abstract excerpt

A combined analysis of two polymorphic enzymes, glutathione S-transferase mu (GST M1) and q (GST T1) and their implication as cancer risk factors was performed in a case-control study of lung and bladder cancers. Using a multiplex polymerase chain reaction (PCR) based method, the frequency of the...

Topics

Aged
Case-Control Studies
Female
Genotype
Glutathione Transferase
Humans
Isoenzymes
Lung Neoplasms
Male
Middle Aged
Polymorphism, Genetic
Risk Factors
Smoking
Urinary Bladder Neoplasms

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