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Article

A germline homozygote deletion of the glutathione-S-transferase Mu1 gene predisposes to bladder cancer.

Urologia internationalis - 1 Jan 2000

Mungan N A, Aben K K, Beeks E, Kampman E, Bunschoten A, Bussemakers M, Witjes J A, Kiemeney L A

Abstract excerpt

INTRODUCTION AND OBJECTIVES: Numerous studies have shown smoking and specific occupational exposures to be risk factors for bladder cancer. The risk of bladder cancer may be modified by the activity of carcinogen metabolizing enzymes. The glutathione-S-transferase Mu1 enzyme (GSTM1) detoxifies arylepoxides which are formed after exposure to certain polycyclic aromatic hydrocarbons and possibly aromatic amines....

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Source

Identifiers

PMID: 10859543
DOI: 10.1159/000030513

Genes

GSTM1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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