Article
9p21 deletions in primary melanoma.
Dermatology online journal - 1 Dec 1997
Naylor M F, Brown S, Quinlan C, Pitha J V, Evertt M A
Abstract excerpt
Formalin-fixed, paraffin-embedded primary melanoma biopsies were evaluated for evidence of genomic loss on the short arm of chromosome 9 using microsatellite PCR assays for the D9S157, D9S161 and D9S171 loci. Paired normal and tumor DNA was extracted from the same block for comparison of microsat...
Topics
- Alleles
- Chromosome Deletion
- DNA, Neoplasm
- Genetic Markers
- Humans
- Melanoma
- Microsatellite Repeats
- Polymerase Chain Reaction
- Skin Neoplasms
