Article
9p21 deletions in primary melanoma.
Dermatology online journal - 1 Dec 1997
Naylor M F, Brown S, Quinlan C, Pitha J V, Evertt M A
Abstract excerpt
Formalin-fixed, paraffin-embedded primary melanoma biopsies were evaluated for evidence of genomic loss on the short arm of chromosome 9 using microsatellite PCR assays for the D9S157, D9S161 and D9S171 loci. Paired normal and tumor DNA was extracted from the same block for comparison of microsatellite marker patterns. Some detectable abnormality was seen in at least one of these loci in 15 of 44 evaluable...
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