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Article

Use of drug-resistance mutants to identify functional regions in picornavirus capsid proteins.

Archives of virology. Supplementum - 1 Jan 1994

Mosser A G, Shepard D A, Rueckert R R

Abstract excerpt

The WIN drugs and similar hydrophobic compounds that insert into the capsid of picornaviruses have been shown to block viral uncoating. In some of the human rhinoviruses they also block attachment of virus to cells. Spontaneously occurring drug-resistant mutants of human rhinovirus 14 and poliovirus type 3 were selected for their ability to make plaques in the presence of the selecting drug. The HRV-14 mutants...

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Source

Identifiers

PMID: 8032243
DOI: 10.1007/978-3-7091-9326-6_12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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