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Article

WIN 52035-dependent human rhinovirus 16: assembly deficiency caused by mutations near the canyon surface.

Journal of virology - 1 Feb 1998

Wang W, Lee W M, Mosser A G, Rueckert R R

Abstract excerpt

Three drug-dependent mutants of human rhinovirus 16 (HRV16) were characterized by sequence analyses of spontaneous mutant isolates and were genetically reconstructed from a parental cDNA plasmid. These mutants formed plaques in the presence but not in the absence of the selecting antiviral drug,...

Topics

Antiviral Agents
Humans
Isoxazoles
Models, Molecular
Mutation
Rhinovirus
Virion
Virus Assembly

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 9445020
DOI: 10.1128/JVI.72.2.1210-1218.1998
PMCID: PMC124598

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9445020-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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