Article
Mes2, a MADF-containing transcription factor essential for Drosophila development.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 2006
Zimmermann Gregor, Furlong Eileen E, Suyama Kaye, Scott Matthew P
Abstract excerpt
The development of the Drosophila mesoderm is initiated by the basic helix-loop-helix transcription factor twist. We identified a gene encoding a putative transcription factor, mes2, in a screen for essential mesoderm-expressed genes that function downstream of twist. Mes2 protein belongs to a family of 48 Drosophila proteins containing MADF domains. MADF domains exist in worms, flies, and fish. Mes2 is a nuclear...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.