Article
Transforming growth factor beta 1 costimulated growth and regulatory function of staphylococcal enterotoxin B-responsive CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 1995
Rich S, Seelig M, Lee H M, Lin J
Abstract excerpt
Transforming growth factor beta (TGF-beta) exhibits diverse effects on growth and differentiation of a wide range of cell types. In the immune system, TGF-beta 1 is a potent inhibitor of T cell proliferation and certain T cell effector functions. However, TGF-beta 1 also enhances growth of T cell...
Topics
- Animals
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Cytokines
- Cytotoxicity, Immunologic
- Enterotoxins
- Lymphocyte Activation
- Male
- Mice
- Mice, Inbred BALB C
- Phenotype
- Signal Transduction
- Staphylococcus aureus
- Superantigens
- Transforming Growth Factor beta