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Article

Superantigen-reactive T cells that display an anergic phenotype in vitro appear functional in vivo.

International immunology - 1 Jan 1995

Heeg K, Gaus H, Griese D, Bendigs S, Miethke T, Wagner H

Abstract excerpt

Clonal deletion and/or inactivation establishes tolerance to self antigens. Endogenous and exogenous (bacterial) superantigens, like the staphylococcal enterotoxins, induce ligand-specific clonal anergy in vivo and thus are believed to mirror aspects of post-thymic tolerance mechanisms in mature peripheral T cells. Here we analyzed the level of anergy of ligand-responsive V beta 8+ T cells from staphylococcal...

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Identifiers

PMID: 7718507
DOI: 10.1093/intimm/7.1.105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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