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Article

Ras mutations in methylclofenapate-induced B6C3F1 and C57BL/10J mouse liver tumours.

Carcinogenesis - 1 Jun 1994

Stanley L A, Blackburn D R, Devereaux S, Foley J, Lord P G, Maronpot R R, Orton T C, Anderson M W

Abstract excerpt

The majority of genotoxic carcinogen-induced liver tumours of the sensitive B6C3F1 mouse contain activated H-ras oncogenes. Such mutations also occur in hepatocarcinogenesis-resistant strains. In order to determine whether this is true of non-genotoxic carcinogen-induced tumours, liver tumours induced in B6C3F1 and C57BL/10J mice by methylclofenapate (MCP) were compared. Polymerase chain reaction (PCR) analysis...

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PMID: 8020144
DOI: 10.1093/carcin/15.6.1125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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