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Article

Mutations in the Ha-ras proto-oncogene in spontaneous and chemically induced liver tumours of the CF1 mouse.

Carcinogenesis - 1 Oct 1990

Bauer-Hofmann R, Buchmann A, Wright A S, Schwarz M

Abstract excerpt

Mutations in codon 61 of the Ha-ras proto-oncogene have been shown to occur with a high frequency in both spontaneous and carcinogen-induced liver tumours of the B6C3F1 mouse. In the present study we analysed the frequency and pattern of Ha-ras mutations in liver tumours in a different strain of mice, namely the CF1 mouse. These liver tumours occurred spontaneously or after administration of either aflatoxin B1,...

Topics

Aflatoxin B1
Aflatoxins
Animals
Base Sequence
Carcinogens
DNA, Neoplasm
Dieldrin
Genes, ras
Liver Neoplasms
Mice
Mice, Inbred Strains
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Oligonucleotide Probes

Phenobarbital

Polymerase Chain Reaction

Source

Identifiers

PMID: 2119910
DOI: 10.1093/carcin/11.10.1875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2119910-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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