Article
Axonal and neuromuscular synaptic phenotypes in Wld(S), SOD1(G93A) and ostes mutant mice identified by fiber-optic confocal microendoscopy.
Molecular and cellular neurosciences - 1 Dec 2009
Wong Frances, Fan Li, Wells Sara, Hartley Robert, Mackenzie Francesca E, Oyebode Oyinlola, Brown Rosalind, Thomson Derek, Coleman Michael P, Blanco Gonzalo, Ribchester Richard R
Abstract excerpt
We used live imaging by fiber-optic confocal microendoscopy (CME) of yellow fluorescent protein (YFP) expression in motor neurons to observe and monitor axonal and neuromuscular synaptic phenotypes in mutant mice. First, we visualized slow degeneration of axons and motor nerve terminals at neurom...
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