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Article

An 85-kb tandem triplication in the slow Wallerian degeneration (Wlds) mouse.

Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 1998

Coleman M P, Conforti L, Buckmaster E A, Tarlton A, Ewing R M, Brown M C, Lyon M F, Perry V H

Abstract excerpt

Wallerian degeneration is the degeneration of the distal stump of an injured axon. It normally occurs over a time course of around 24 hr but it is delayed in the slow Wallerian degeneration mutant mouse (C57BL/Wlds) for up to 3 weeks. The gene, which protects from rapid Wallerian degeneration, Wld, previously has been mapped to distal chromosome 4. This paper reports the fine genetic mapping of the Wld locus, the...

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Identifiers

PMID: 9707587
DOI: 10.1073/pnas.95.17.9985
PMCID: PMC21448

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