Article
An 85-kb tandem triplication in the slow Wallerian degeneration (Wlds) mouse.
Proceedings of the National Academy of Sciences of the United States of America - 18 Aug 1998
Coleman M P, Conforti L, Buckmaster E A, Tarlton A, Ewing R M, Brown M C, Lyon M F, Perry V H
Abstract excerpt
Wallerian degeneration is the degeneration of the distal stump of an injured axon. It normally occurs over a time course of around 24 hr but it is delayed in the slow Wallerian degeneration mutant mouse (C57BL/Wlds) for up to 3 weeks. The gene, which protects from rapid Wallerian degeneration, Wl...
Topics
- Alleles
- Animals
- Base Sequence
- Chromosome Mapping
- Crossing Over, Genetic
- DNA Primers
- Gene Rearrangement
- Mice
- Mice, Inbred C57BL
- Mice, Neurologic Mutants
- Molecular Sequence Data
- Multigene Family
- Mutation
- Polymerase Chain Reaction
- Recombination, Genetic