Human cytotrophoblast cells cultured in maternal serum progress to a differentiated syncytial phenotype expressing both human chorionic gonadotropin and human placental lactogen.

doi:10.1210/endo.135.1.8013368

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Article

Human cytotrophoblast cells cultured in maternal serum progress to a differentiated syncytial phenotype expressing both human chorionic gonadotropin and human placental lactogen.

Endocrinology - 1 Jul 1994

Richards R G, Hartman S M, Handwerger S

Abstract excerpt

Under appropriate conditions, protease-dispersed cytotrophoblast cells from human term placenta fuse and differentiate into syncytiotrophoblast cells that express hCG. Although human placental lactogen (hPL) is also expressed by the syncytiotrophoblast in vivo, little hPL is expressed by trophobl...

Topics

Blood
Cell Differentiation
Cells, Cultured
Chorionic Gonadotropin
Culture Media
Female
Humans
Phenotype
Placental Lactogen
Pregnancy
RNA, Messenger
Trophoblasts

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