Article
Analysis of regional differences of p53 mutation in advanced gastric carcinoma: relation to heterogeneous differentiation and invasiveness.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Feb 1994
Cho J H, Noguchi M, Ochiai A, Uchino S, Hirohashi S
Abstract excerpt
In order to examine the correlation of p53 mutation with heterogeneous histological differentiation and invasiveness of gastric carcinoma, we analyzed 46 areas (three to six per case) that were different histologically and anatomically in 12 advanced gastric carcinomas, shown previously to be pos...
Topics
- Base Sequence
- Carcinoma
- DNA Primers
- DNA, Neoplasm
- Electrophoresis, Polyacrylamide Gel
- Genes, p53
- Humans
- Immunoenzyme Techniques
- Molecular Sequence Data
- Mutation
- Neoplasm Invasiveness
- Polymerase Chain Reaction
- Stomach Neoplasms
- Tumor Suppressor Protein p53