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Article

Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana.

Molecular and biochemical parasitology - 1 Feb 1994

Souza A E, Bates P A, Coombs G H, Mottram J C

Abstract excerpt

The parasitic protozoon Leishmania mexicana possesses an abundance of developmentally regulated cathepsin L-like cysteine proteinases expressed at highest levels in amastigotes. We recently characterised lmcpa, a single-copy gene encoding one such proteinase, LmCPa, which differs from other homol...

Topics

Alleles
Animals
Base Sequence
Blotting, Western
Cathepsin L
Cathepsins
Cinnamates
Cysteine Endopeptidases
Drug Resistance
Endopeptidases
Genes, Protozoan
Genetic Markers
Hygromycin B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leishmania mexicana

Molecular Sequence Data

Mutagenesis, Insertional

Mutation

Phenotype

Source

Identifiers

PMID: 8008019
DOI: 10.1016/0166-6851(94)90057-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8008019-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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