Article
Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana.
Molecular and biochemical parasitology - 1 Feb 1994
Souza A E, Bates P A, Coombs G H, Mottram J C
Abstract excerpt
The parasitic protozoon Leishmania mexicana possesses an abundance of developmentally regulated cathepsin L-like cysteine proteinases expressed at highest levels in amastigotes. We recently characterised lmcpa, a single-copy gene encoding one such proteinase, LmCPa, which differs from other homologues by possessing a 3-amino-acid insertion at the amino terminal of the predicted mature proteinase. To investigate...
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