Article
Homologues of LMPK, a mitogen-activated protein kinase from Leishmania mexicana, in different Leishmania species.
Medical microbiology and immunology - 1 Nov 2001
Wiese M, Görcke I
Abstract excerpt
LMPK, a mitogen-activated protein (MAP) kinase homologue of Leishmania mexicana, is essential for the proliferation of the amastigote, the mammalian stage of the protozoan parasite. This has been demonstrated using deletion mutant promastigotes, the insect stage of the parasite: first, in vitro after differentiation to amastigotes, which subsequently lost their potential to proliferate; second, by infection of...
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