Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion of the gene for the membrane-bound acid phosphatase of Leishmania mexicana.

Molecular and biochemical parasitology - 1 Nov 2000

Benzel I, Weise F, Wiese M

Abstract excerpt

The membrane-bound acid phosphatase of Leishmania mexicana (LmxMBAP) has been shown to be a heterogeneously N-glycosylated type I transmembrane protein, which is localized predominantly in vesicular structures close to the flagellar pocket in promastigotes and amastigotes. Its expression in both life stages prompted us to analyse its function by performing deletion analysis. Both alleles of the single copy gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acid Phosphatase
Share to Gene Targeting
Share to Genes, Protozoan

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, rRNA

Share to Leishmaniasis, Cutaneous

Share to Macrophages

Share to Mice, Inbred BALB C

Share to Protozoan Proteins

Source

Identifiers

PMID: 11087918
DOI: 10.1016/s0166-6851(00)00306-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion of the gene for the membrane-bound acid phosphatase of Leishmania mexicana.PMID 11087918Read ↗

Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana.Semantic proximity Read ↗

Characterisation of a Leishmania mexicana knockout lacking guanosine diphosphate-mannose pyrophosphorylase.Semantic proximity Read ↗

Glycosylation defects and virulence phenotypes of Leishmania mexicana phosphomannomutase and dolicholphosphate-mannose synthase gene deletion mutants.Semantic proximity Read ↗

Disruption of mannose activation in Leishmania mexicana: GDP-mannose pyrophosphorylase is required for virulence, but not for viability.Semantic proximity Read ↗

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.Semantic proximity Read ↗

The role of GlcNAc-PI-de-N-acetylase gene by gene knockout through homologous recombination and its consequences on survival, growth and infectivity of Leishmania major in in vitro and in vivo conditions.Semantic proximity Read ↗

Biochemical characterization of Leishmania major aquaglyceroporin LmAQP1: possible role in volume regulation and osmotaxis.Semantic proximity Read ↗

Identification and Characterization of a Protein-tyrosine Phosphatase in LeishmaniaSemantic proximity Read ↗

Phenotypic characterization of a glucose transporter null mutant in Leishmania mexicana.Semantic proximity Read ↗

Homologues of LMPK, a mitogen-activated protein kinase from Leishmania mexicana, in different Leishmania species.Semantic proximity Read ↗

Interplay between a cytosolic and a cell surface carbonic anhydrase in pH homeostasis and acid tolerance of Leishmania.Semantic proximity Read ↗

Protein kinase involved in flagellar-length control.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.