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Article

Definition of regions of the human genome affected by loss of heterozygosity in primary human breast tumors.

Journal of cellular biochemistry. Supplement - 1 Jan 1993

Callahan R, Cropp C, Sheng Z M, Merlo G, Steeg P, Liscia D, Lidereau R

Abstract excerpt

We have undertaken a systematic study of primary human breast tumor DNA to identify and characterize frequently occurring somatic mutations. Loss of heterozygosity (LOH) has been the most frequent mutation in our panels of primary breast tumor DNA. It is currently thought that LOH reveals recessive mutations within the affected region of the genome. One goal of our studies has been to physically define the target...

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Identifiers

PMID: 8007695
DOI: 10.1002/jcb.240531131

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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