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Article

Effects of the maleless mutation on X and autosomal gene expression in Drosophila melanogaster.

Genetics - 1 Mar 1994

Hiebert J C, Birchler J A

Abstract excerpt

The mutational effect of the maleless (mle) gene in Drosophila has been reexamined. Earlier work had suggested that mle along with other male-lethal genes was responsible for hypertranscription of the X chromosome in males to bring about dosage compensation. Prompted by studies on dosage sensitive regulatory genes, we tested for effects of mlets on the phenotypes of 16 X or autosomal mutations in adult escapers...

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Identifiers

PMID: 8005444
DOI: 10.1093/genetics/136.3.913
PMCID: PMC1205896

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