Effects of the maleless mutation on X and autosomal gene expression in Drosophila melanogaster.

doi:10.1093/genetics/136.3.913

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Article

Effects of the maleless mutation on X and autosomal gene expression in Drosophila melanogaster.

Genetics - 1 Mar 1994

Hiebert J C, Birchler J A

Abstract excerpt

The mutational effect of the maleless (mle) gene in Drosophila has been reexamined. Earlier work had suggested that mle along with other male-lethal genes was responsible for hypertranscription of the X chromosome in males to bring about dosage compensation. Prompted by studies on dosage sensitiv...

Topics

Animals
Biological Evolution
Dosage Compensation, Genetic
Drosophila melanogaster
Eye Color
Female
Gene Expression Regulation
Genes, Insect
Genes, Lethal
Homozygote
Larva
Male
Mutation
Phenotype
RNA, Messenger
Transcription, Genetic
Wings, Animal
X Chromosome

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