Article
Specificity, sensitivity, and predictive value of apolipoprotein-E genotyping for sporadic Alzheimer's disease.
Lancet (London, England) - 13 Jul 1996
Saunders A M, Hulette O, Welsh-Bohmer K A, Schmechel D E, Crain B, Burke J R, Alberts M J, Strittmatter W J, Breitner J C, Rosenberg C
Abstract excerpt
BACKGROUND: We aimed to determine the specificity, sensitivity, and predictive value of apolipoprotein E (APOE) genotyping in 67 consecutive patients with clinical diagnoses of sporadic Alzheimer's disease (AD) who underwent necropsy. METHODS: We studied patients who attended the Duke Memory Diso...
Topics
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Base Sequence
- Genotype
- Humans
- Molecular Sequence Data
- Predictive Value of Tests
- Sensitivity and Specificity