Article
Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield.
Applied and environmental microbiology - 1 Nov 1994
Patnaik R, Liao J C
Abstract excerpt
Escherichia coli and many other microorganisms synthesize aromatic amino acids through the condensation reaction between phosphoenolpyruvate (PEP) and erythrose 4-phosphate to form 3-deoxy-D-arabinoheptulosonate 7-phosphate (DAHP). It has been shown that overexpression of transketolase increases...
Topics
- Culture Media
- Escherichia coli
- Gene Expression Regulation, Enzymologic
- Genetic Engineering
- Glucose
- Mutation
- Phosphoenolpyruvate Carboxylase
- Phosphotransferases (Paired Acceptors)
- Sugar Phosphates