Article
A direct comparison of approaches for increasing carbon flow to aromatic biosynthesis in Escherichia coli.
Journal of industrial microbiology - 1 Jul 1996
Gosset G, Yong-Xiao J, Berry A
Abstract excerpt
Different approaches to increasing carbon commitment to aromatic amino acid biosynthesis were compared in isogenic strains of Escherichia coli. In a strain having a wild-type PEP:glucose phosphotransferase (PTS) system, inactivation of the genes encoding pyruvate kinase (pykA and pykF) resulted in a 3.4 fold increase in carbon flow to aromatic biosynthesis. In a strain already having increased carbon flow to...
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