Article
Inactivation of the PTS as a Strategy to Engineer the Production of Aromatic Metabolites in Escherichia coli.
Journal of molecular microbiology and biotechnology - 1 Jan 2015
Carmona Susy Beatriz, Moreno Fabián, Bolívar Francisco, Gosset Guillermo, Escalante Adelfo
Abstract excerpt
Laboratory and industrial cultures of Escherichia coli employ media containing glucose which is mainly transported and phosphorylated by the phosphotransferase system (PTS). In these strains, 50% of the phosphoenolpyruvate (PEP), which results from the catabolism of transported glucose, is used as a phosphate donor for its phosphorylation and translocation by the PTS. This characteristic of the PTS limits the...
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