Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synthetic methanol auxotrophy of Escherichia coli for methanol-dependent growth and production.

Metabolic engineering - 1 Sept 2018

Chen Chang-Ting, Chen Frederic Y-H, Bogorad Igor W, Wu Tung-Yun, Zhang Ruoxi, Lee Abraxa S, Liao James C

Abstract excerpt

Methanol is a potentially attractive substrate for bioproduction of chemicals because of the abundance of natural gas and biogas-derived methane. To move towards utilizing methanol as a sole carbon source, here we engineer an Escherichia coli strain to couple methanol utilization with growth on five-carbon (C5) sugars. By deleting essential genes in the pentose phosphate pathway for pentose utilization and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Escherichia coli
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ethanol

Share to Genome, Bacterial

Share to Methanol

Share to Mutation

Share to Operon

Source

Identifiers

PMID: 30172686
DOI: 10.1016/j.ymben.2018.08.010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synthetic methanol auxotrophy of Escherichia coli for methanol-dependent growth and production.PMID 30172686Read ↗

Growth of E. coli on formate and methanol via the reductive glycine pathway.Semantic proximity Read ↗

A new carbon catabolite repression mutation of Escherichia coli, mlc∗, and its use for producing isobutanol.Semantic proximity Read ↗

Global Functional Analysis of Butanol-Sensitive Escherichia coli and Its Evolved Butanol-Tolerant Strain.Semantic proximity Read ↗

Construction and evolution of an Escherichia coli strain relying on nonoxidative glycolysis for sugar catabolism.Semantic proximity Read ↗

Use of catabolite repression mutants for fermentation of sugar mixtures to ethanol.Semantic proximity Read ↗

Metabolic engineering of Escherichia coli for acetaldehyde overproduction using pyruvate decarboxylase from Zymomonas mobilis.Semantic proximity Read ↗

A systematic analysis of TCA Escherichia coli mutants reveals suitable genetic backgrounds for enhanced hydrogen and ethanol production using glycerol as main carbon source.Semantic proximity Read ↗

Eliminating acetate formation improves citramalate production by metabolically engineered Escherichia coli.Semantic proximity Read ↗

Engineering of Escherichia coli central metabolism for aromatic metabolite production with near theoretical yield.Semantic proximity Read ↗

Biosensor-Based Directed Evolution of Methanol Dehydrogenase from Lysinibacillus xylanilyticus.Semantic proximity Read ↗

Identification of Enzymatic Bottlenecks for the Aerobic Production of Malate from Glycerol by the Systematic Gene Overexpression of Anaplerotic Enzymes in Escherichia coli.Semantic proximity Read ↗

Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.