Article
(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer.
Proceedings of the National Academy of Sciences of the United States of America - 6 Dec 1994
Zenklusen J C, Bièche I, Lidereau R, Conti C J
Abstract excerpt
Loss of heterozygosity in human chromosome 7q was studied to determine the location of a putative tumor suppressor gene. Twenty-six of 31 cases studied presented loss of heterozygosity at one or more loci on chromosome 7q. Eighty-three percent loss of heterozygosity (in 11 informative cases) was detected by using the (C-A)n microsatellite repeat marker D7S522 at 7q31.1-7q31.2. These results suggest that a tumor...
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