Two discrete regions of deletion at 7q in uterine leiomyomas.

doi:10.1002/(sici)1098-2264(199707)19:3<156::aid-gcc4>3.0.co;2-x

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Article

Two discrete regions of deletion at 7q in uterine leiomyomas.

Genes, chromosomes & cancer - 1 Jul 1997

Ishwad C S, Ferrell R E, Hanley K, Davare J, Meloni A M, Sandberg A A, Surti U

Abstract excerpt

This study further defines the region of consistent deletion of chromosome 7 in uterine leiomyomas. We have examined 74 leiomyomas for allelic loss of markers spanning the 7q22 region defined by markers D7S518 and D7S471. Forty tumors with cytogenetically defined 7q deletions, twenty-nine tumors...

Topics

Alleles
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 7
DNA, Neoplasm
Female
Gene Deletion
Heterozygote
Humans
Karyotyping
Leiomyoma
Microsatellite Repeats
Polymerase Chain Reaction
Uterine Neoplasms

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