Frequent loss of heterozygosity at 7q31.1 in primary prostate cancer is associated with tumor aggressiveness and progression.

Article

Frequent loss of heterozygosity at 7q31.1 in primary prostate cancer is associated with tumor aggressiveness and progression.

Cancer research - 15 Sept 1995

Takahashi S, Shan A L, Ritland S R, Delacey K A, Bostwick D G, Lieber M M, Thibodeau S N, Jenkins R B

Abstract excerpt

Cytogenetic analyses have demonstrated that chromosome region 7q22-32 is commonly altered in prostate adenocarcinomas. In addition, in recent fluorescence in situ hybridization studies, we have observed that aneusomy of chromosome 7 is frequent in prostate cancer and is associated with higher tum...

Topics

Alleles
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 7
Humans
Male
Polymerase Chain Reaction
Prostatic Neoplasms

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