Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer.

Lancet (London, England) - 18 Jan 1992

Bièche I, Champème M H, Matifas F, Hacène K, Callahan R, Lidereau R

Abstract excerpt

Genetic alterations are believed to be important in the origin and dissemination of breast cancer. Cytogenetic rearrangements on chromosome 7 are common in breast tumours. We used the c-met proto-oncogene probe, which detects sequences on chromosome 7q31, to analyse tumour and blood leucocyte DNA samples from 245 patients with primary breast cancers. The pmetH polymorphic probe detected a high frequency of allele...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Breast Neoplasms
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Heterozygote

Share to Mutation

Share to Polymorphism, Restriction Fragment Length

Share to Proto-Oncogene Proteins

Source

Identifiers

PMID: 1346009
DOI: 10.1016/0140-6736(92)90208-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer.PMID 1346009Read ↗

(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer.Semantic proximity Read ↗

Germline large genomic alterations on 7q in patients with multiple primary cancers.Semantic proximity Read ↗

Allelic loss at 7q31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene.Semantic proximity Read ↗

Allelotyping of acute myelogenous leukemia: loss of heterozygosity at 7q31.1 (D7S486) and q33-34 (D7S498, D7S505).Semantic proximity Read ↗

Mutational analysis of the ST7 gene in human myeloid tumor cell lines.Semantic proximity Read ↗

Genomic structure and expression profile of LPHH1, a 7TM gene variably expressed in breast cancer cell lines.Semantic proximity Read ↗

Loss of c-met protooncogene in primary and metastatic sites of breast cancer.Semantic proximity Read ↗

Identification of a 1300 kilobase deletion unit on chromosome 7q31.3 in invasive epithelial ovarian carcinomas.Semantic proximity Read ↗

Genetic and molecular heterogeneity of breast cancer cells.Semantic proximity Read ↗

Frequent somatic imbalance of marker alleles for chromosome 1 in human primary breast carcinoma.Semantic proximity Read ↗

Loss of heterozygosity on chromosome 9 in human breast cancer: association with clinical variables and genetic changes at other chromosome regions.Semantic proximity Read ↗

Chromosome 7q31 allelic imbalance and somatic mutations of RAY1/ST7 gene in colorectal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.